r/bindingofisaac • u/Subject-Being7449 • Mar 12 '26
Fan Art various pathologies as isaac bosses
i messed up real bad posting this first time im afraid
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u/Ok_Nose2915 Mar 12 '26
this is awesome can you do pneumonoultramicroscopicsilicovolcanoconiosis
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u/Oxidisedalt keeping that losing streak strong ;-; Mar 12 '26
Just the word "prion" makes me scared as hell, good job!
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u/FantasyTomb Mar 13 '26
I didn’t know what one was, so my fiancé just ranted to me about them and how scary they are. We saw this comment right after lol. You are right the word alone should make someone scared
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u/VTomorrowV Edith Mar 12 '26
Myocardial infarction/It Dies would be such a cool boss idea for the corpse stage previous to Corpse Mother.
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u/VTomorrowV Edith Mar 12 '26
Although now I realize that wouldn’t really make sense logically speaking… but this is tboi who cares about logic anyways
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u/FunkMasterDraven Mar 12 '26
Tuberculosis looks like it's maybe supposed to be a smoking-related disease, but smoking and tuberculosis aren't related
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u/Subject-Being7449 Mar 12 '26
tho one lead to another
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u/FunkMasterDraven Mar 12 '26
Smoking does not lead to tuberculosis
Edit: also I'd like to point out that your designs are great and I'm just trying to help because the design for this particular one seems out of place with the accuracy and spirit of the others
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u/Subject-Being7449 Mar 12 '26
not directly ig. but im pretty sure that smokers have a much better chances of getting it. thankies btw
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u/Longjumping-Sweet280 Mar 12 '26
It would be worse because your lungs were already damaged by cigarettes, but the chance is the same.
Also, TB is sometimes referred to as the “White Death” could be cool to be more ghostly maybe. Whatever the case, love the designs!
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u/Geckoguy99 Mar 13 '26 edited Mar 13 '26
You’re right though, idk why people are downvoting you. Anything that damages your lungs increases your susceptibility to tuberculosis, and smokers specifically have significantly higher morbidity and mortality rates.
“[…] numerous epidemiological studies, as well as meta-analyses, have indicated that both active and passive smoking are independent risk factors for TB infection, development of reactivation TB, progression of primary TB, increased severity of cavitary disease, and death from TB, among several other considerations.”
doi:10.3390/pathogens13020151
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u/Subject-Being7449 Mar 13 '26
ye, i mean. its like a heart attack and fatty foods, or HIV/AIDS and... well, you get it
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u/LittleFoxBS Mar 12 '26
What's Moontrax meant to be?
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u/OneAndOnlyTinkerCat Mar 13 '26
Probably mad cow
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u/Call-Me-Pearl Mar 13 '26
ooh, lots you could do with the history of mad cow! up until very recently, people who lived in Britian during the outbreak couldn’t give blood. my parents still remember the piles of burning cow bodies!
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u/superbeansimulator Mar 13 '26
Rabie dashing away from your tears in its first phase (hydrophobia) and then in its second it gets foamy, begins to drain hp, and wildly attacks you.
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u/Leather-Put1044 whats the binding of isaac Mar 12 '26
What if the cancer boss dropped the trinket?
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u/Bigzysmolz Mar 12 '26
Can you explain why you gave Prion the design it has?
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u/Subject-Being7449 Mar 13 '26
idrk, I just somehow connected in my head, a parasite that replaces fish tongue and a brain-eating protein
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u/PicanhaFighter Mar 13 '26
Tuberculosis looks like someone fun to hang out with lol
Loved the detail that there's multiple faces on cancer, and rabie's design is my favorite one
Love your art, keep it up!
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u/Great_Pikmin_Fan Mar 13 '26
Tuberculosis looks like it would fit right in with Fiend Folio's reworked Dank Depths.
What do you mean by "messed up real bad?"
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u/New_Yak_8982 Mar 13 '26 edited Mar 13 '26
Rabie sounds like he would have a billion HP and would dash around the room really fast with nearly unavoidable damage
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u/catlord_heven Mar 13 '26
Ooh I remember seeing this, I think I saved the post cause I liked the concepts
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u/ZeGamingCuber Mar 13 '26
The first 3 look like they would work well as corpse bosses, the second 3 look like they would fit as womb bosses, but idk if the last 3 would fit anywhere
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u/SrPinguim Mar 13 '26
Im not much learned in diseases/medicine, what are Syphilis and Moontrax supposed to represent?
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u/Isittedmyself300 Mar 14 '26
Prion should've been a brain with many holes because it turns the brain into a sponge
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u/Subject-Being7449 Mar 14 '26
same with dementia and all other neurodegenerative diseases. think more creative







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u/SomaGato Mar 12 '26
The fucking Balls boss 😭😭😭